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Earth, Air, Fire, and Water
How One Molecule Connects the Minerals of Earth, the Gases of Air, the Heat of Fire, and Intelligence of the Living Cell The natural world is not a collection of isolated substances but a system of interacting elements. Modern chemistry, geology, atmospheric science, and molecular biology have revealed that water plays a remarkable role in connecting these different domains. Water dissolves the minerals of the Earth, absorbs and exchanges the gases of the atmosphere, stores a
jonlieff
2 days ago15 min read


The Intelligence of Water - Aquaporins and the Medium That Participates in the Computation
The Intelligence of Water: What Aquaporins Reveal The argument that water possesses a form of molecular intelligence begins with its unusual physical properties. Water molecules respond to their surroundings, interact cooperatively, and continuously change their arrangements. Their positive and negative electrical regions allow them to form hydrogen bonds that break and reform within trillionths of a second. These interactions allow water molecules to respond rapidly to nearb
jonlieff
7 days ago15 min read


Molecular Mind in Cellular Motors 3: Disordered Dancing Molecules Allow for Infinite Agility and Creativity
Since DNA’s discovery, molecular biology had operated on reassuring assumptions: every protein folds into one precise, stable shape; shape determines its function; and shape is determined by a sequence of amino acids produced by a sequence of DNA letters. It was a clean idea. The holy grail of bioscience for decades was finding the shapes of proteins and the DNA codes that determine that shape. It is very difficult to determine the shapes of any protein from the sequence of a

Jon Lieff
May 134 min read


Molecular Mind in Cellular Motors 2: Water, The Universal, Dynamic, Non-covalent, Weak Bonds for all of Life’s Activity
Water is the medium that makes life possible. Water is so ordinary that we rarely think of it as doing anything. But inside a living cell, water is not a passive background—it is an active participant in nearly every molecular event and every cellular structure. The water molecule has a peculiar geometry. One oxygen atom pulls so strongly on two hydrogen atoms that it ends up slightly negative, while the two hydrogens are left slightly positive, which results in four partial

Jon Lieff
May 94 min read
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